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Research

Airway Microbiota Dynamics Uncover a Critical Window for Interplay of Pathogenic Bacteria and Allergy in Childhood Respiratory Disease

To complement early allergic sensitization, monitoring NPM composition may enable early detection and intervention in high-risk children

Research

Prevalence of allergic sensitization, hay fever, eczema, and asthma in a longitudinal birth cohort

The aim of this study was to longitudinally assess the prevalence of allergic sensitization, asthma, eczema and hay fever from infancy to adulthood

Research

A platform for discovery of functional cell-penetrating peptides for efficient multi-cargo intracellular delivery

This report thus establishes a discovery platform for identifying novel, functional CPPs to expand the delivery landscape of druggable intracellular targets for biological therapeutics

Research

Pre-service teachers: Knowledge, attitudes and their perceived skills in addressing student bullying

The lack of skills in managing future bullying and particularly cyberbullying incidents reported by pre-service teachers has social and emotional implications for young people

Research

Transketolase and vitamin B1 influence on ROS-dependent neutrophil extracellular traps (NETs) formation

The regulation of Transketolase by oxythiamine and/or vitamin B1 may therefore be associated with response to the modulation of NET formation

Research

Efficacy of oral amoxicillin-clavulanate or azithromycin for non-severe respiratory exacerbations in children with bronchiectasis (BEST-1)

Amoxicillin-clavulanate treatment is beneficial in terms of resolution of non-severe exacerbations of bronchiectasis in children

Research

Choosing primary endpoints for clinical trials of health care interventions

This narrative review describes the evolution, range and relative strengths and weaknesses of endpoints used in late phase trials

Research

Role of pre-existing adversity and child maltreatment on mental health outcomes for children involved in child protection: population-based data linkage study

Young people who have been involved in the child protection system are at increased risk for mental health events and diagnoses

Research

Mapping the global endemicity and clinical burden of Plasmodium vivax, 2000-17: a spatial and temporal modelling study

Our study highlights important spatial and temporal patterns in the clinical burden and prevalence of P vivax

Research

Implementing and Evaluating Interventions to Improve School Readiness and Early Literacy

The implementation of the Pacific early age readiness and learning program has generated significant data, evidence, operational experience, and knowledge