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novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunctionThis study thus identified a novel small molecule that rapidly kills MLL-rearranged leukemia cells by targeting a metabolic vulnerability
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Improving self-regulation and executive functioning skills in primary school children in a remote Australian Aboriginal community: A pilot study of the Alert Program®This community partnered pilot research, evaluated a school-based program to reduce the behavioral impact of fetal alcohol spectrum disorder
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Children and adolescents with type 1 diabetes in Australasia: An online survey of model of care, workforce and outcomesSurvey of the model of care and workforce that manages children and adolescents with type 1 diabetes in Australasia along with glycaemic outcomes
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Mapping changes in housing in sub-Saharan Africa from 2000 to 2015Our maps provide a baseline for measuring change and a mechanism to guide interventions during the era of the Sustainable Development Goals
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Prediction modelling using routine clinical parameters to stratify survival in Malignant Pleural Mesothelioma patients undergoing cytoreductive surgeryThe CART model was able to stratify surgical patients into risk groups with statistically different survival characteristics with fair to good performance
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Differential SLC6A4 methylation: a predictive epigenetic marker of adiposity from birth to adulthoodThese data suggest that altered methylation of CpG loci within SLC6A4 may provide a robust marker of adiposity across the life course
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The effect of aquatic high-intensity interval training on aerobic performance, strength and body composition in a non-athletic populationIn a non-athletic population, aquatic-high-intensity interval training was safe and may have improved aerobic performance and lower limb strength
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Higher non-processed red meat consumption is associated with a reduced risk of central nervous system demyelinationWe found no statistically significant association between processed red meat density and risk of a first clinical diagnosis of central nervous system demyelination
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Extreme heat threatens the health of AustraliansHeatwaves have serious health impacts and we need a better approach to prevention and management
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Multiple-breath washout outcomes are sensitive to inflammation and infection in children with cystic fibrosisThe lung clearance index may be a useful surveillance tool for monitoring the presence and extent of lower airway inflammation and infection