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Research

Single-cell transcriptomic and spatial landscapes of the developing human pancreas

Current differentiation protocols have not been successful in reproducibly generating fully functional human beta cells in vitro, partly due to incomplete understanding of human pancreas development. Here, we present detailed transcriptomic analysis of the various cell types of the developing human pancreas, including their spatial gene patterns. We integrated single-cell RNA sequencing with spatial transcriptomics at multiple developmental time points and revealed distinct temporal-spatial gene cascades.

Research

Rare disease education in Europe and beyond: time to act

People living with rare diseases (PLWRD) still face huge unmet needs, in part due to the fact that care systems are not sufficiently aligned with their needs and healthcare workforce (HWF) along their care pathways lacks competencies to efficiently tackle rare disease-specific challenges. Level of rare disease knowledge and awareness among the current and future HWF is insufficient.

Research

Parental Perspectives on Children’s School Readiness: An Ethnographic Study

School readiness is a construct used by educators and policy makers to describe a range of abilities that are beneficial for children transitioning to school. The association of socioeconomic disadvantage with developmental vulnerability when children start school is well established. Parents play a crucial role in supporting children’s transition to school and are acknowledged as their child’s first and foremost teacher.

Research

Antimicrobial susceptibility testing profiles of ESBL-producing Enterobacterales isolated from hospital and community adult patients in Blantyre, Malawi

There is a paucity of data on antimicrobial resistance (AMR) in Malawi. Here we present a study of AMR of extended-spectrum β-lactamases-producing Enterobacterales (ESBL-E) isolated from hospital and community settings in Blantyre, Malawi.

Research Theme

Wellbeing and Mental Health

Our Wellbeing and Mental Health research focuses on improving the emotional and psychological health of children. We develop evidence-based interventions and strategies to promote resilience, prevent mental health challenges, and help kids thrive.

Research

Ngulluk Koolunga Ngulluk Koort (Our Children, Our Heart) Program

Brings the Aboriginal community(s) of Perth together with service providers & policy makers to improve outcomes for Aboriginal kids and their families.

News & Events

Building a secure attachment with your child

Secure attachments help children build resilience, self-worth, emotion regulation skills and healthy relationships.

Strategic Plan 2019-2023

At The Kids, our vision is simple - happy healthy kids. We bring together community, researchers, practitioners, policy makers and funders, who share our mission to improve the health, development and lives of children and young people through excellence in research.

Annual Report 2013

The Kids Research Institute Australia's annual report highlights the accomplishments of our researchers, furthering our mission to secure a happier, healthier future for kids everywhere.