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Research
New therapeutic opportunities from dissecting the pre-B leukemia bone marrow microenvironmentWe provide evidence that targeting leukemia-induced bone loss is a therapeutic strategy for pre-B ALL
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Association between male genital anomalies and adult male reproductive disorders: a population-based data linkage study spanning more than 40 yearsWe provide new evidence to support current guidelines for orchidopexy before age 18 months to decrease the risk of future testicular cancer and infertility
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High Dose Vitamin D supplementation alters faecal microbiome and predisposes mice to more severe colitisHigh dose vitamin D supplementation is associated with a shift to a more inflammatory faecal microbiome and increased susceptibility to colitis
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Out-of-Home Care and the Educational Achievement, Attendance, and Suspensions of Maltreated Children: A Propensity-Matched StudyOut-of-home care was not found to be a significant factor in the adverse educational outcomes of these children
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Candidate gene testing in clinical cohort studies with multiplexed genotyping and mass spectrometryWe describe a cost-effective tag single nucleotide polymorphism approach using a multiplexed genotyping assay with mass spectrometry
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Appendicular fracture epidemiology of children and adolescents: a 10-year case review in Western Australia (2005 to 2015)Increased fracture incidence in Western Australia between 2005 and 2015 identifies a concerning trend for bone health in children and adolescents
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Symptom severity in autism spectrum disorder is related to the frequency and severity of nausea and vomiting during pregnancy: a retrospective case-control studyInvestigating whether the presence and severity of nausea and vomiting may be related to symptom severity in offspring with autism spectrum disorder
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The impact of psychotic experiences in the early stages of mental health problems in young peoplePsychotic experiences appear to be particularly associated with depressive symptoms and psychological distress, impaired role functioning and quality of life in help-seeking young people in the medium-term
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Maternal high fat diet compromises survival and modulates lung development of offspring, and impairs lung function of damsWhile maternal high fat diet compromised litter survival, it also promoted somatic and lung growth (increased lung volume) in the offspring
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PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding proteinA novel mouse model for glioma demonstrating that the PI3K pathway is important for initiation of tumorigenesis