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Research

Early progressive encephalopathy in boys and MECP2 mutations

MECP2 mutations mainly occur in females with Rett syndrome. Mutations have been described in 11 boys with progressive encephalopathy...

Research

NTNG1 mutations are a rare cause of Rett syndrome

A translocation that disrupted the netrin G1 gene (NTNG1) was recently reported in a patient with the early seizure variant of Rett syndrome (RTT).

Research

Screening for retinopathy of prematurity to prevent blindness (RETCAM)

Retinopathy of prematurity (ROP) is an eye disease that can occur in premature babies. It causes abnormal blood vessels to grow in the retina, and

Research

Characterization of “bystander” effects of the diphtheria-pertussis-tetanus (DTP) vaccine on the IgE system

We are seeking more detailed information on how the immune system of infants responds to the vaccine, with the aim of identifying which aspects of the immune r

Research

Family Study of Ear Health and Metabolic Diseases in a Western Australian Aboriginal Community

To determine whether these extreme manifestations of disease are associated with rare or novel genetic variants in a Western Australian Aboriginal population.

MECP2 duplication syndrome (MDBase)

MECP2 duplication syndrome is a rare disorder neurodevelopmental disorder that, unlike Rett syndrome, mostly affects boys.

Research snapshots

Our research covers a broad range of areas from the influence of mutation type on health outcomes to factors impacting on the lives of familes.

Altered attainment of developmental milestones

Regression, including the loss of previously learned skills, such as hand function and communication skills, is one of the most suggestive features of Rett synd

Validating the Rett Syndrome Gross Motor Scale

Our study investigated the quality of measurements obtained using the Rett Syndrome Gross Motor Scale.