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Research

Interpregnancy interval and adverse birth outcomes: a population-based cohort study of twins

To investigate associations between interpregnancy intervals (IPIs) and adverse birth outcomes in twin pregnancies.

Research

The collaboration on social science and immunisation (COSSI): Global lessons from a successful Australian research and practice network

Samantha Carlson BSc MPH PhD Senior Research Officer Samantha.carlson@thekids.org.au Senior Research Officer @samicarlson ORCID Dr Carlson is an

Research

A systematic search and narrative review of Aboriginal and Torres Strait Islander women and men pelvic health care: demonstrated need for improvement

Pelvic health conditions among Aboriginal and Torres Strait Islander women and men are under-recognised and under-reported despite indication of the significant burden of these conditions. Access to effective management provided in a culturally safe manner appears lacking.

Research

High-dose chemotherapy for Ewing sarcoma and Rhabdomyosarcoma: A systematic review by the Australia and New Zealand sarcoma association clinical practice guidelines working party

Patients with high-risk or metastatic Ewing sarcoma (ES) and rhabdomyosarcoma (RMS) have a guarded prognosis. High-dose chemotherapy (HDT) with autologous stem cell transplant (ASCT) has been evaluated as a treatment option to improve outcomes. However, survival benefits remain unclear, and treatment is associated with severe toxicities.

Research

A Deep Learning-Based System for the Assessment of Dental Caries Using Colour Dental Photographs

Dental caries remains the most common chronic disease in childhood, affecting almost half of all children globally. Dental care and examination of children living in remote and rural areas is an ongoing challenge that has been compounded by COVID.

Research

Nanoremediation Associated with Microorganisms

Environmental pollution has a detrimental effect on human health. Short and long-term exposure to harmful pollutants can lead to serious ailments and incurable diseases. Consequently, it is necessary to manage the environmental contaminants to mitigate or even eliminate the deleterious effects to living beings.

Research

Behavior Change Techniques Involved in Physical Activity Interventions for Children with Chronic Conditions: A Systematic Review

Behavior change techniques (BCTs) have been extensively used in physical activity interventions for children, however, no systematic reviews have synthesized their effects.

Research

Symbiotic symphony: Understanding host-microbiota dialogues in a spatial context

Modern precision sequencing techniques have established humans as a holobiont that live in symbiosis with the microbiome. Microbes play an active role throughout the life of a human ranging from metabolism and immunity to disease tolerance. Hence, it is of utmost significance to study the eukaryotic host in conjunction with the microbial antigens to obtain a complete picture of the host-microbiome crosstalk. 

Research

Mapping Lung Hematopoietic Progenitors: Developmental Kinetics and Response to Influenza A Infection

The bone marrow is a specialised niche responsible for the maintenance of hematopoietic stem and progenitor cells during homeostasis and inflammation. Recent studies however have extended this essential role to the extramedullary and extravascular lung microenvironment. Here, we provide further evidence for a reservoir of hematopoietic stem and progenitor cells within the lung from embryonic day 18.5 until adulthood.

Research

Patient-Derived Orthotopic Xenograft Models for High-Grade Pediatric Brain Cancers

Patient-derived orthotopic xenograft (PDOX) mouse models are considered the gold standard for evidence-based preclinical research in pediatric neuro-oncology. This protocol describes the generation of PDOX models by intracranial implantation of human pediatric brain cancer cells into immune-deficient mice, and their continued propagation to establish cohorts of animals for preclinical research.

News & Events

Research buddies make a difference

What is a research buddy and how you can be involved?

News & Events

What the national Consumer Involvement Committee have been working on

The Centre’s Community Involvement Framework is underpinned by the principles of being inclusive, working together, learning and development, two-way communication, evaluation and impact and strong governance structure.

News & Events

Congratulations 2024 Seed Funding Recipients!

The Rio Tinto Children’s Diabetes Centre; a JDRF Global Centre of Excellence announces $60,000 in new round of seed grants for researchers dedicated to type 1 diabetes. Three researchers from across Australia have received up to $20,000 to advance their research projects in type 1 diabetes (T1D). 

News & Events

Student Scholarships

The Centre aims to improve the lives of young people living with diabetes by encouraging new and innovative research, researchers and translation

News & Events

Research Newsletter Coming

The Rio Tinto Children's Diabetes Centre will soon launch a newsletter dedicated to informing the community, our global researchers and our

News & Events

Community involvement opportunity - Research Buddies

Become a Research Buddy Ever wanted to be involved in type 1 diabetes research studies, but never knew how to get started or never had time before

News & Events

World Diabetes Day fundraisers across WA

Last month we celebrated World Diabetes Day and what a monumental day it was. This year's theme was 'Access to diabetes care' and the WA T1D community spread the message far and wide.

News & Events

Community Forum Recording

The Rio Tinto Children's Diabetes Centre, A JDRF Global Centre of Excellence COMMUNITY FORUM - Wednesday 26 July, 2023 Thank you to all those who

News & Events

Nutrition videos

Nutrition videos for young people living with T1D Australian children living with type 1 diabetes (T1D) and their families can now access trustworthy