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Research

novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

This study thus identified a novel small molecule that rapidly kills MLL-rearranged leukemia cells by targeting a metabolic vulnerability

Research

Mapping changes in housing in sub-Saharan Africa from 2000 to 2015

Our maps provide a baseline for measuring change and a mechanism to guide interventions during the era of the Sustainable Development Goals

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Differential SLC6A4 methylation: a predictive epigenetic marker of adiposity from birth to adulthood

These data suggest that altered methylation of CpG loci within SLC6A4 may provide a robust marker of adiposity across the life course

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Standardizing clinical care measures of rheumatic heart disease in pregnancy: A qualitative synthesis

Pregnancy provides an opportunity to strengthen health system responses and address whole-of-life health for women with rheumatic heart disease

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Trial refresh: A case for an adaptive platform trial for pulmonary exacerbations of cystic fibrosis

This review will discuss the necessary steps required for a Bayesian adaptive platform trial to optimize treatment of pulmonary exacerbations of cystic fibrosis

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Controlled human infection for vaccination against Streptococcus pyogenes (CHIVAS): Establishing a group A Streptococcus pharyngitis human infection study

We review the Group A Streptococcus Human infection studies and present the study protocol for a dose-ranging inpatient study in healthy adults

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Discrete choice experiment to evaluate preferences of patients with cystic fibrosis among alternative treatment-related health outcomes: A protocol

The aim of this study is to identify and quantify the preferences of patients with cystic fibrosis regarding treatment outcomes

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Narrative Medicine Meets Planetary Health: Mindsets Matter in the Anthropocene

We argue that the principles and practice of narrative medicine can be applied on a larger scale, one with planetary health in mind

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Improving self-regulation and executive functioning skills in primary school children in a remote Australian Aboriginal community: A pilot study of the Alert Program®

This community partnered pilot research, evaluated a school-based program to reduce the behavioral impact of fetal alcohol spectrum disorder

Research

Children and adolescents with type 1 diabetes in Australasia: An online survey of model of care, workforce and outcomes

Survey of the model of care and workforce that manages children and adolescents with type 1 diabetes in Australasia along with glycaemic outcomes