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Expression Levels of Therapeutic Targets as Indicators of Sensitivity to Targeted TherapeuticsWe investigated the relationship between the sensitivity of hundreds of cell lines to hundreds of drugs, and the relative expression levels of the targets
Research
Sun exposure: An environmental preventer of metabolic dysfunction?Emerging preclinical findings suggest that some sun exposure is necessary for optimal metabolic health
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Early patterns of functional brain development associated with autism spectrum disorder in tuberous sclerosis complexInfants with Tuberous sclerosis complex demonstrated reduced interhemispheric alpha phase coherence compared to controls at 12 months of age
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Intrauterine growth restriction affects diaphragm function in adult female and male miceSex and intrauterine growth restriction independently affect diaphragm contraction in adult mice without changes in structure
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Impact of the “balatrine” intervention on soil-transmitted helminth infections in central Java, Indonesia: A pilot studyThe integrated BALatrine intervention was associated with a reduced incidence of soil-transmitted helminth infection
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Prevalence of Group A β-hemolytic Streptococcal Throat Carriage and Prospective Pilot Surveillance of Streptococcal Sore Throat in Ugandan School ChildrenThe Group A β-hemolytic Streptococcus pharyngeal carriage rates seen in Uganda (15.9%) are higher than the most recent pooled results globally, at 12%
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Transcriptional blood signatures for active and amphotericin B treated visceral leishmaniasis in IndiaAmphotericin B provides improved therapy for visceral leishmaniasis (VL) caused by Leishmania donovani
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Challenges to curing primary brain tumoursThe seven key challenges summarized in this Position Paper are intended to serve as foci for future research and investment in brain tumours
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Cyclin-Dependent Kinase-Like 5 Deficiency Disorder: Clinical ReviewClinical presentations and genetic variations in Cyclin-dependent kinase-like 5 deficiency disorder based on a systematic literature review and experience
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Selection of appropriate spirometry reference values in Aboriginal AustraliansThe Global Lung Function ‘Caucasian’ and ‘Other’ spirometry equations do not match healthy Aboriginal FEV1 and FVC data