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Ivacaftor or lumacaftor/ivacaftor treatment does not alter the core CF airway epithelial gene response to rhinovirus

We tested the hypothesis that treatment of CF epithelial cells with ivacaftor (Iva) or ivacaftor/lumacaftor (Iva/Lum) would improve control of rhinovirus infection.

News & Events

Research into innovative treatments for people with asthma and antibiotic resistance supported by Innovation Fellowships

Two outstanding researchers from the Wal-yan Respiratory Research Centre have been awarded a 2022 Innovation Fellowship supported by the WA Government's Future Health Research and Innovation (FHRI) Fund.

News & Events

Kids Easy Breathing Study Kickstarts

The Kids Easy Breathing Study kickstarts this month, with the aim of finding out how the airway surface is different between infants who develop chronic lung disease after contracting bronchiolitis compared with those who don’t.

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Unique twin study reveals clues to childhood allergies

A study published in Science Advances has revealed that while genetics play a significant role in shaping children's immune systems, environmental factors also influence key immune responses, offering opportunity for preventing allergic diseases.

Use of a Primary Epithelial Cell Screening Tool to Investigate Phage Therapy in Cystic Fibrosis

Use of a Primary Epithelial Cell Screening Tool to Investigate Phage Therapy in Cystic Fibrosis Antimicrobial-resistant microbes are an increasing

Investigating self-efficacy, disease knowledge and adherence to treatment in adolescents with cystic fibrosis

Investigating self-efficacy, disease knowledge and adherence to treatment in adolescents with cystic fibrosis Aim: Patient adherence is integral to

Metabolomic Biomarkers Predictive of Early Structural Lung Disease in Cystic Fibrosis.

Metabolomic Biomarkers Predictive of Early Structural Lung Disease in Cystic Fibrosis. ABSTRACT Neutrophilic airway inflammation plays a role in

Oxidative stress and abnormal bioactive lipids in early cystic fibrosis lung disease

Oxidative stress and abnormal bioactive lipids in early cystic fibrosis lung disease. What did you find? We focused on lipid molecules which we know

Regional differences in infection and structural lung disease in infants and young children with cystic fibrosis

This study aimed to explore the links between infection and where early damage due to CF is found in young children with CF. The results showed that