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Subcutaneous infusion of high-dose benzathine penicillin G is safe, tolerable, and suitable for less-frequent dosing for rheumatic heart disease secondary prophylaxis: a phase 1 open-label population pharmacokinetic studySince 1955, the recommended strategy for rheumatic heart disease secondary prophylaxis has been benzathine penicillin G injections administered intramuscularly every 4 weeks. Due to dosing frequency, pain, and programmatic challenges, adherence is suboptimal. It has previously been demonstrated that BPG delivered subcutaneously at a standard dose is safe and tolerable and has favorable pharmacokinetics, setting the scene for improved regimens with less frequent administration.
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Research opportunities for the primordial prevention of rheumatic fever and rheumatic heart disease - streptococcal vaccine development: a national heart, lung and blood institute workshop reportStreptococcus pyogenes, also known as group A streptococcus (StrepA), is a bacterium that causes a range of human diseases, including pharyngitis, impetigo, invasive infections, and post-infection immune sequelae such as rheumatic fever and rheumatic heart disease. StrepA infections cause some of the highest burden of disease and death in mostly young populations in low-resource settings. Despite decades of effort, there is still no licensed StrepA vaccine, which if developed, could be a cost-effective way to reduce the incidence of disease.
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Building social and emotional wellbeing through the artsThe ‘Building Social and Emotional Wellbeing Through the Arts Project’ was funded in 2021 by Healthway and supported through a partnership between The Kids Research Institute Australia and Edith Cowan University (ECU).
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Alert Program®Emma Glenn Martyn Adams Pearson Symons BExSc, MPH BA (Education) PhD Candidate B.A. (Hons) PhD. Acting Research Officer; PhD student Director of
Within the Institute, we have a commitment to the highest standards of research with pro-active staff ensuring the lab environment is safe and secure.
More than 3,000 skin checks have been undertaken as part of a large clinical trial in WA’s Kimberley region aimed at halving the burden of skin sores in school-aged Aboriginal children.
Young people and their families have teamed up with youth mental health providers and researchers to deliver a report which tackles youth suicide in WA.
Alarming statistics laying bare the social emotional wellbeing and mental health challenges facing Aboriginal and Torres Strait Islander LGBTQA+ youth are driving a multi-partner program to provide them with greater support.
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CybersafetyEven in the safety of their home, there are many risky places a child or teenager can visit online. This can be due to the content they see, who they come into contact with, and personal information they share.
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Fetal Alcohol Spectrum Disorder (FASD)Fetal Alcohol Spectrum Disorder (FASD) is a lifelong condition characterised by severe neurodevelopmental impairment due to prenatal exposure to alcohol.