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Perturbation of the T Cell Compartment Underlies Rheumatic Fever Pathogenesis

This prospective cohort study, which recruited participants with definite ARF in Australia and Aotearoa New Zealand, profiled circulating immune molecules and cells to inform disease mechanisms and future druggable pathways.

Diverse diagnostic and management approaches for acute rheumatic fever in Australia and New Zealand: findings of a prospective clinical study

This study provides new knowledge on ARF characteristics and management and highlights international variation in diagnostic and management practice.

Searching for a technology-driven acute rheumatic fever test: the START study protocol

The absence of a diagnostic test for acute rheumatic fever (ARF) is a major impediment in managing this serious childhood condition. ARF is an autoimmune condition triggered by infection with group A Streptococcus.

Noeletta McKenzie

Noeletta McKenzie is a Champion for Change, RHDAustralia, and community representative and advocate for the START study.

Margaret and Liana

Liana’s story begins nine years ago. It starts with a sore ankle, a fever, a trip to the emergency room and clinic and finally a diagnosis of acute rheumatic fever (ARF).