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Intrauterine growth restriction affects diaphragm function in adult female and male miceSex and intrauterine growth restriction independently affect diaphragm contraction in adult mice without changes in structure
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Boosting airway T-regulatory cells by gastrointestinal stimulation as a strategy for asthma controlThe hallmark of atopic asthma is transient airways hyperresponsiveness (AHR) preceded by aeroallergen-induced Th-cell activation.
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Risk assessment for respiratory complications in paediatric anaesthesia: a prospective cohort studyPerioperative respiratory adverse events in children are one of the major causes of morbidity and mortality during paediatric anaesthesia.
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Stiffness Mediated-Mechanosensation of Airway Smooth Muscle Cells on Linear Stiffness Gradient HydrogelsIn obstructive airway diseases such as asthma and chronic obstructive pulmonary disease (COPD), the extracellular matrix (ECM) protein amount and composition of the airway smooth muscle (ASM) is often remodelled, likely altering tissue stiffness. The underlying mechanism of how human ASM cell (hASMC) mechanosenses the aberrant microenvironment is not well understood.
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Quantifying airway remodelling for research or clinical purposes: How should we normalize for airway size?Citation: Donovan GM, Wang KCW, Elliot JG, James AL, Noble PB. Quantifying airway remodelling for research or clinical purposes: How should we
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Genome Sequences of Two Lytic Staphylococcus aureus Bacteriophages Isolated from WastewaterTwo lytic double-stranded DNA (dsDNA) bacteriophages, belonging to the family Herelleviridae, were isolated from wastewater in Western Australia. Biyabeda-mokiny 2 appears to belong to the genus Kayvirus, and Koomba-kaat 1 to Silviavirus.
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The effects of acamprosate on maternal and neonatal outcomes in a mouse model of alcohol use disordersDespite the teratogenic effects of alcohol, little is known about the safety of pharmacotherapies such as acamprosate for the treatment of alcohol use disorders in pregnancy. The aims of this study were to investigate, in a mouse model, the effects of maternally administered acamprosate on maternal and neonatal health, offspring neurodevelopment and behaviour, as well as examine whether acamprosate reduces the neurological harm associated with alcohol consumption in pregnancy.
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Fetal alcohol exposure, nutritional status and epigenetic disruption – exploring the linksAlexander David Martyn Larcombe Martino Symons BScEnv (Hons) PhD BSc PhD B.A. (Hons) PhD. Honorary Research Fellow Head, Chronic Diseases Research
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The health effects of electronic cigarettesAlexander Larcombe BScEnv (Hons) PhD Honorary Research Fellow Honorary Research Fellow Associate Professor Alexander Larcombe began work at The Kids
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The effects of electronic cigarette aerosol exposure on inflammation and lung function in miceThis study shows, for the first time, that exposure to e-cigarette aerosol during adolescence and early adulthood is not harmless to the lungs and can result in significant impairments in lung function.