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Research

Editorial overview: Endocrine and metabolic adaptations to extreme environments: Living life to the extreme – insights into the limits of life and transitions to disease

The need to understand responses to extreme environments has prompted this edition of Current Opinion in Endocrine and Metabolic Research

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Pharmacological ablation of the airway smooth muscle layer—Mathematical predictions of functional improvement in asthma

Findings provide further proof of concept that pharmacological targeting of airway smooth muscle thickness will be beneficial and may be facilitated by azithromycin

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Independent and combined effects of airway remodelling and allergy on airway responsiveness

There was a positive relationship between the thickness of the airway smooth muscle layer with airway responsiveness, which was shifted upward in the presence of allergy

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The effects of electronic cigarette aerosol exposure on inflammation and lung function in mice

This study shows, for the first time, that exposure to e-cigarette aerosol during adolescence and early adulthood is not harmless to the lungs and can result in significant impairments in lung function.

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Fragranced consumer products: effects on asthmatic Australians

Most asthmatics would prefer workplaces, healthcare facilities, and environments that are fragrance-free, which could help reduce adverse effects

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A cross-sectional survey of environmental health in remote Aboriginal communities in Western Australia

Poor environmental health is prevalent in remote Aboriginal communities and requires further delineation to inform environmental health policy

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Early life rhinovirus infection exacerbates house-dust-mite induced lung disease more severely in female mice

Early life rhinovirus infection influences the development of house-dust-mite induced lung disease in female, but not male mice

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The effect of diesel exhaust exposure on blood-brain barrier integrity and function in a murine model

Epidemiological studies indicate that exposure to diesel exhaust (DE) is associated with vascular-based disorders.

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Risk assessment for respiratory complications in paediatric anaesthesia: a prospective cohort study

Perioperative respiratory adverse events in children are one of the major causes of morbidity and mortality during paediatric anaesthesia.

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Emerging Early Life Environmental Exposures and Lung Development

In this review article we systematically summarize the evidence for an impact on lung development of 1) maternal ingestion of arsenic contaminated drinking...