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Research

Increased CTLA-4+ T cells may contribute to impaired T helper type 1 immune responses in patients with chronic obstructive pulmonary disease

Chronic inflammation may expand sub-populations of T cells expressing CTLA-4 in COPD patients and therefore impair T-cell function

Research

The 2015 Middle Childhood Survey (MCS) of mental health and well-being at age 11 years in an Australian population cohort

most children report mental health and well-being, but the population distribution spanned the full range of possible scores on every construct.

Research

The role of preschool quality in promoting child development: evidence from rural Indonesia

This article examines the relationship between preschool quality and children’s early development in a sample of over 7900 children enrolled in 578 preschools in rural Indonesia.

Research

Vaccine hesitancy, refusal and access barriers: The need for clarity in terminology

We propose more precision in the term 'vaccine hesitancy' is needed particularly since much under-vaccination arises from factors related to access

Research

Long-term outcomes from acute rheumatic fever and rheumatic heart disease

Adverse outcomes for people with acute rheumatic fever and rheumatic heart disease and the effect of comorbidities and demographic factors on these outcomes

Research

Autism Spectrum Disorder, Language Disorder, and Social (Pragmatic) Communication Disorder: Overlaps, Distinguishing Features, and Clinical Implications

Strictly defined cases of social (pragmatic) communication disorder and specific language impairment can be distinguished from autism spectrum disorder

Research

A genome-wide approach to children's aggressive behavior: The EAGLE consortium

Common variants at 2p12 show suggestive evidence for association with childhood aggression

Research

Early Nutrition as a Major Determinant of 'Immune Health': Implications for Allergy, Obesity and Other Noncommunicable Diseases

A better understanding of nutritional programming of immune health may lead to dietary strategies that reduce the burden of many inflammatory diseases

Research

Effects of maltreatment and parental schizophrenia spectrum disorders on early childhood social-emotional functioning: a population record linkage study

Childhood maltreatment and history of parental SSD are associated independently with poor early childhood social-emotional functioning