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Research

Immune Responses to Allergens in Atopic Disease: Considerations for Bioinformatics

Allergies are mediated by several immunological mechanisms that make different contributions in different patients.

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Distinguishing benign from pathologic TH2 immunity in atopic children

In addition to its role in blocking TH2 effector activation in the late-phase allergic response, IL-10 is a known IgG1 switch factor

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Update of the WHO/IUIS Allergen Nomenclature Database based on analysis of allergen sequences

This paper summarizes updates of allergen names approved at the meetings of the IUIS Allergen Nomenclature Sub-Committee in 2011 through 2013.

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Molecular characterization of Der p 10: A diagnostic marker for broad sensitization in house dust mite allergy

Tropomyosins represent clinically relevant seafood allergens but the role of mite tropomyosin

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CD4 allergen tetramers

The introduction of class II tetramers for identifying antigen-binding CD41 cells has lagged behind the use of class I tetramers because of difficulties...

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Effect of early carriage of streptococcus pneumoniae on the development of pneumococcal protein-specific cellular immune responses in infancy

The aim of this study was to examine the relationship between nasopharyngeal pneumococcal colonization in early life and the development of T cell responses.

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The Western Environment Reduces Innate Immune Cytokine Production in Chinese Immigrants

We recruited age- and sex-matched Chinese immigrants living in Western Australia for less than 6 months (newly arrived, n = 22) or more than 5 years.

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WHO/IUIS Allergen Nomenclature: Providing a common language

Aim was to standardize the names given to the antigens (allergens) that caused IgE-mediated allergies in humans

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A longitudinal study of natural antibody development to pneumococcal surface protein A families 1 and 2 in Papua New Guinean Highland children: a cohort study

Pneumococcal surface protein A is immunogenic and natural anti-PspA immune responses are acquired through exposure and develop with age

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Immunodominant T-cell epitopes in the VP1 capsid protein of rhinovirus species A and C

Our results indicate a dissociation between the antibody and T-cell responses to rhinoviruses