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Research
Increased CTLA-4+ T cells may contribute to impaired T helper type 1 immune responses in patients with chronic obstructive pulmonary diseaseChronic inflammation may expand sub-populations of T cells expressing CTLA-4 in COPD patients and therefore impair T-cell function
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Premedication with salbutamol prior to surgery does not decrease the risk of perioperative respiratory adverse events in school-aged childrenPremedication with salbutamol to children prior to their surgery did not reduce their risk of Perioperative respiratory adverse events
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Characteristics associated with clinical severity and inflammatory phenotype of naturally occurring virus-induced exacerbations of asthma in adultsType 2 inflammation is present in patients during virus-induced asthma exacerbations, to the same degree as non-viral exacerbations
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Distress and psychological morbidity do not reduce over time in carers of patients with high-grade gliomahis study aimed to determine how carer distress and psychological morbidity change over time following a patient's diagnosis of high-grade glioma
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Induced sputum to detect lung pathogens in young children with cystic fibrosiswe aimed to determine the sensitivity and specificity of induced sputum with and without airway clearance techniques to detect lower airway pathogens in kids.
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Using record linkage to validate notification and laboratory data for a more accurate assessment of notifiable infectious diseasesStudies investigating pathogen-specific infectious disease would benefit from using multiple data sources.
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Introducing ‘Young Minds Matter’This article describes the survey, the response rates achieved and the representativeness of the sample for the Young Minds Matter survey
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No evidence for impaired humoral immunity to pneumococcal proteins in Australian Aboriginal children with otitis mediaConserved vaccine candidate proteins from S.pneumoniae induce serum and salivary antibody responses in Aboriginal and non-Aboriginal children with history of OM
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Influence of maternal obesity on the long-term health of offspringIncluding immediate implications for pregnancy complications, increasing evidence implicates maternal obesity having a major impact on long term child health.
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Patterns of multiple risk exposures for low receptive vocabulary growth 4-8 years in the Longitudinal Study of Australian ChildrenOur results demonstrate a range of multiple risk profiles in a population-representative sample of Australian children and highlight the mix of risk factors faced by children