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The anti-inflammatory effects of interleukin-4 are not mediated by suppressor of cytokine signalling-1 (SOCS1)While it is known that the anti-inflammatory effects of interleukin (IL)-4 require new protein synthesis, the exact mechanisms by which IL-4 suppresses the prod
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Th2-associated immunity to bacteria in asthma in teenagers and susceptibility to asthmaBacterial colonisation of the airways is associated with increased risk of childhood asthma
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Randomized controlled trial of early regular egg intake to prevent egg allergyWe aimed to determine whether regular consumption of egg protein from 4-6 month old reduced the risk of IgE-mediated egg allergy in infants without eczema.
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Chinese immigrants in Australia at higher risk of allergies, research showsChinese immigrants who live in a Western environment like Australia have an increased risk of allergies, hay fever and asthma, new research led by Curtin University and The Kids Research Institute Australia has found.
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The cat lipocalin Fel d 7 and its cross-reactivity with the dog lipocalin Can f 1Fel d 7 is a common allergen in a Swedish cat-sensitized population that cross-reacts with Can f 1
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Distinguishing benign from pathologic TH2 immunity in atopic childrenIn addition to its role in blocking TH2 effector activation in the late-phase allergic response, IL-10 is a known IgG1 switch factor
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Molecular characterization of Der p 10: A diagnostic marker for broad sensitization in house dust mite allergyTropomyosins represent clinically relevant seafood allergens but the role of mite tropomyosin
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CD4 allergen tetramersThe introduction of class II tetramers for identifying antigen-binding CD41 cells has lagged behind the use of class I tetramers because of difficulties...
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Preparing for Life: Plasma Proteome Changes and Immune System Development During the First Week of Human LifeNeonates have heightened susceptibility to infections. The biological mechanisms are incompletely understood but thought to be related to age-specific adaptations in immunity due to resource constraints during immune system development and growth. We present here an extended analysis of our proteomics study of peripheral blood-plasma from a study of healthy full-term newborns delivered vaginally, collected at the day of birth and on day of life (DOL) 1, 3, or 7, to cover the first week of life. The plasma proteome was characterized by LC-MS using our established 96-well plate format plasma proteomics platform.