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Research

Propofol use in children with allergies to egg, peanut, soybean or other legumes

We conclude that genuine serious allergic reaction to propofol is rare and is not reliably predicted by a history of food allergy

Research

PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumours

Our findings define PTPN2 as a target for bolstering T-cell-mediated anti-tumour immunity and CAR T-cell therapy against solid tumours.

Research

Nasal Cytokine Profiles of Patients Hospitalised with Respiratory Wheeze Associated with Rhinovirus C

Medically attended RV-C-induced wheeze is characterised by a Th2 inflammatory pattern, independent of viral load

Research

Genome mining and characterisation of a novel transaminase with remote stereoselectivity

Here we report a novel ω-transaminase discovered in a marine sponge Pseudovibrio sp. isolate

Research

Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment

Our results identify a pretreatment tumor microenvironment that predicts response to immune checkpoint blockade, which can be therapeutically attained

Research

The Australian and New Zealand Children's Haematology/Oncology Group Biobanking Network

The ANZCHOG-BN is a new biobank network in Australasia that was developed to improve and streamline access to high-quality pediatric and AYA cancer biospecimens

Research

Impact of Micronutrient Status during Pregnancy on Early Nutrition Programming

Globally and even in high-income countries where a balanced diet is generally accessible, an inadequate maternal micronutrient status is common

Research

The Nature and Quality of Australian Supermarkets' Policies that can Impact Public Health Nutrition, and Evidence of their Practical Application: A Cross-Sectional Study

Findings suggest Australian supermarket CSR policies are not likely to adequately contribute to improving population diets or sustainability of food systems

Research

Developmental vulnerabilities in children of chronically ill parents: A population-based linked data study

Maternal chronic illness is associated with an increased risk of poor developmental outcomes for children, particularly daughters

Research

Individualized prediction of transition to psychosis in 1,676 individuals at clinical high risk: Development and validation of a multivariable prediction model

The aim of the study was to develop and validate an individualized, clinically based prognostic model for forecasting transition to psychosis from a CHR-P stage