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These findings suggest that tumor cells employ multiple epigenetic and genetic mechanisms to evade immune control
Our findings provide insight into the immune cell populations important for maintaining long-term tumour dormancy in peripheral tissues
In this review, we discuss the different subsets of tumor-infiltrating dendritic cells and their role in anti-tumor immunity
Our data demonstrate that CD8+XCR1neg DCs possess a unique pattern of endocytic receptors and a restricted TLR profile that is particularly enriched for TLR5
Our results show that TRM cells have a fundamental role in the surveillance of subclinical melanomas in the skin by maintaining cancer-immune equilibrium
Our findings present a novel mouse model for glioma demonstrating that the PI3K pathway is important for initiation of tumorigenesis
Data indicate a role for Interferonβ in linking viral infection and allergy
Early changes in cell morphology upon treatments are a strong indication that the inhibitor is directly targeting tubulin
These findings implicate the activation of STAT3 as one pathway that may mediate resistance to IGF-II-targeted therapy in HCC
Invasive fungal disease (IFD) occurs less frequently during treatment for solid compared to hematological malignancies in children, and risk groups are poorly defined. Retrospective national multicenter cohort data (2004-2013) were analyzed to document prevalence, clinical characteristics, and microbiology of IFD.