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The relationship between early life episodes of otitis media and later behavioural development with adjustment for confounders.
To assess the effectiveness of antibiotics versus antiseptics for people with chronic suppurative otitis media.
To assess the effects of topical antiseptics for people with chronic suppurative otitis media
To assess the effects of systemic antibiotics for people with chronic suppurative otitis media.
To assess the effects of topical antibiotics for people with chronic suppurative otitis media.
To assess the effects of adding a topical steroid to topical antibiotics in the treatment of people with chronic suppurative otitis media
Otitis media (OM) starts within weeks of birth in almost all Indigenous infants living in remote areas of the Northern Territory (NT).
Otitis media (OM) is a common disease in early childhood characterised by inflammation of the middle ear.
This study was the first to concurrently identify middle ear pathogens in both bacterial biofilm and intracellularly in the middle ear mucosa of children and to identify extensive DNA stranding in the MEF from children with AOM
We identified several novel candidate genes which warrant further analysis in cohorts matched more precisely for clinical phenotypes.