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Epidemiology of seasonal influenza infection in pregnant women and its impact on birth outcomesResults from this linked population study suggests that there are differences in maternal infection by virus type and support the provision of seasonal vaccines
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Correlation of ultra-low dose chest CT findings with physiologic measures of asbestosisThis study aimed to determine the relationship between ULDCT-ILD and measures of pulmonary function in an asbestos-exposed population.
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Early mortality and primary causes of death in mothers of children with intellectual disability or Autism spectrum disorderMothers of children with intellectual disability or autism spectrum disorder (ASD) have poorer health than other mothers.
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School performance in children with type 1 diabetes: a contemporary population-based studyOur aim was to examine the school performance of children with type 1 diabetes in comparison to their peers, exploring changes over time, and the impact of...
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Maternal Dietary Intake of Folate and Vitamins B6 and B12 During Pregnancy and Risk of Childhood Brain TumorsThis Australia-wide study examines whether maternal intake of folate and vitamins B6 and B12 during pregnancy is associated with development of brain tumors...
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Ultraviolet radiation exposure and serum vitamin D levels in young childrenThis paper examined the link between UV exposure and vitamin D production in young children to determine how long it takes for sun exposure to affect serum...
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Mesothelioma risk after 40 years since first exposure to asbestos: A pooled analysisThis paper discusses the risk of developing malignant mesothelioma more than 40 years after the first exposure to asbestos.
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The impact of pandemic A(H1N1)pdm09 influenza and vaccine-associated adverse events on parental attitudes and influenza vaccine uptake in young childrenThis paper reports on the shift in parental attitude to vaccination after 2010, due to an unprecedented increase in febrile reactions in children receiving...
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Small-molecule screen reveals synergy of cell cycle checkpoint kinase inhibitors with DNA-damaging chemotherapies in medulloblastomaMedulloblastoma (MB) consists of four core molecular subgroups with distinct clinical features and prognoses. Treatment consists of surgery, followed by radiotherapy and cytotoxic chemotherapy. Despite this intensive approach, outcome remains dismal for patients with certain subtypes of MB, namely, MYC-amplified Group 3 and TP53-mutated SHH. Using high-throughput assays, six human MB cell lines were screened against a library of 3208 unique compounds. We identified 45 effective compounds from the screen and found that cell cycle checkpoint kinase (CHK1/2) inhibition synergistically enhanced the cytotoxic activity of clinically used chemotherapeutics cyclophosphamide, cisplatin, and gemcitabine.
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Prediction modelling using routine clinical parameters to stratify survival in Malignant Pleural Mesothelioma patients undergoing cytoreductive surgeryThe CART model was able to stratify surgical patients into risk groups with statistically different survival characteristics with fair to good performance