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Research
Updated model of group A Streptococcus M proteins based on a comprehensive worldwide studyGroup A Streptococcus (GAS) M protein is an important virulence factor and potential vaccine antigen, and constitutes the basis for strain typing (emm-typing).
Research
Group A streptococcal vaccines: Paving a path for accelerated developmentVaccine prevention of GAS infections and their immunological complications has been a goal of researchers for decades.
Research
Progress toward a global Group A streptococcal vaccineThe desire for an effective vaccine arises from the large burden of disease caused by the bacterium, particularly rheumatic fever and rheumatic heart disease.
Research
Preventing urinary tract infections in early childhoodUrinary tract infection (UTI) is common in children, causes them considerable discomfort, as well as distress to parents and has a tendency to recur.
Research
A national prospective surveillance study of acute rheumatic fever in Australian childrenAcute rheumatic fever (ARF) is an important cause of heart disease in Indigenous people of northern and central Australia.
Research
Improving Health Outcomes in the Tropical North: A Multidisciplinary Collaboration (HOT NORTH)‘Improving Health Outcomes in the Tropical North’ will strengthen partnerships with key research institutions across the NT, Qld, WA, NSW, Vic and SA, by undertaking an integrated research agenda that will help close the gap in Indigenous health disadvantage, protect the north from emerging infectious threats and
Research
Coalition to Advance Vaccines Against Group A Streptococcus (CANVAS): A Trans-Tasman Initiative Against Rheumatic FeverCANVAS is a commitment by the Governments of Australia and New Zealand to advance the development of a vaccine against GAS infection, which can cause rheumatic fever.
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Developing a human challenge model of GAS infectionNHMRC funding has been awarded for 4 years to Murdoch Childrens Research Institute for this project, with collaboration from Professor Jonathan Carapetis at The Kids.
Research
END RHD Demonstration CommunitiesThe END RHD Communities approach uses community-led, research-backed prevention strategies to tackle Strep A skin and throat infections, acute rheumatic fever and rheumatic heart disease
Research
Penicillin Levels for Rheumatic Heart Disease Study - WA Urban CohortThis is a 6 month cohort study involving participants at Princess Margaret Hospital prescribed BPG for secondary prophylaxis of RHD.