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Protocol for a nested case-control study design for omics investigations in the Environmental Determinants of Islet Autoimmunity cohortThe Environmental Determinants of Islet Autoimmunity (ENDIA) pregnancy-birth cohort investigates the developmental origins of type 1 diabetes (T1D), with recruitment between 2013 and 2019. ENDIA is the first study in the world with comprehensive data and biospecimen collection during pregnancy, at birth and through childhood from at-risk children who have a first-degree relative with T1D.
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Epigenetics of the non-coding RNA nc886 across blood, adipose tissue and skeletal muscle in offspring exposed to diabetes in pregnancyDiabetes in pregnancy is associated with increased risk of long-term metabolic disease in the offspring, potentially mediated by in utero epigenetic variation. Previously, we identified multiple differentially methylated single CpG sites in offspring of women with gestational diabetes mellitus, but whether stretches of differentially methylated regions can also be identified in adolescent GDM offspring is unknown.
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Reproducibility of the plasma glucose response to moderate-intensity exercise in adolescents with Type 1 diabetesThe plasma glucose response to moderate-intensity exercise can be reproducible in adolescents with Type 1 diabetes
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Prevalence of celiac disease in 52,721 youth with type 1diabetes: International comparison across three continentsTim Jones MBBS DCH FRACP MD Co-head, Diabetes and Obesity Research Co-head, Diabetes and Obesity Research Areas of research expertise: Diabetes
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Safety and efficacy of the predictive low glucose management system in the prevention of hypoglycaemiaThe predictive low glucose management system was evaluated in in-clinic studies, and has informed a larger home trial to study its efficacy and safety
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School performance in children with type 1 diabetes: A contemporary population-based studyType 1 diabetes is not associated with a significant decrement in school performance, as assessed by NAPLAN
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Effect of exercise intensity on glucose requirements to maintain euglycemia during exercise in type 1 diabetesInverted-U relationship between exercise intensity and glucose requirement
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Unexpected Management Behaviors in Adolescents With Type 1 Diabetes Using Sensor-Augmented Pump TherapyConstant exposure to real-time data can lead to unsafe management responses in adolescents with the behavior influenced by trust or mistrust in the system
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Severe hypoglycemia rates are not associated with HbA1c: A cross-sectional analysis of 3 contemporary pediatric diabetes registry databasesTo examine the association between glycated hemoglobin (HbA1c) and severe hypoglycemia rates in patients with type 1 diabetes receiving usual care.
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The Importance of the Hawthorne Effect on Psychological Outcomes Unveiled in a Randomized Controlled Trial of Diabetes TechnologyThe objective of this communication is to highlight the Hawthorne effect on psychobehavioral measures and the importance of a control group in clinical research, particularly for diabetes technologies