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Research
PKC activation promotes maturation of cord blood T cells towards a Th1 IFN-γ propensityA significant number of babies present transiently with low protein kinase C zeta (PKCζ) levels in cord blood T cells, associated with reduced ability to transition from a neonatal Th2 to a mature Th1 cytokine bias, leading to a higher risk of developing allergic sensitisation, compared to neonates whose T cells have 'normal' PKCζ levels. However, the importance of PKCζ signalling in regulating their differentiation from a Th2 to a Th1 cytokine phenotype propensity remains undefined.
Research
Urinary Ferritin as a Noninvasive Means of Assessing Iron Status in Young ChildrenIron deficiency (ID) is the most common nutritional deficiency affecting young children. Serum ferritin concentration is the preferred biomarker for measuring iron status because it reflects iron stores; however, blood collection can be distressing for young children and can be logistically difficult. A noninvasive means to measure iron status would be attractive to either diagnose or screen for ID in young children.
Research
“Coronavirus Changed the Rules on Everything”: Parent Perspectives on How the COVID‐19 Pandemic Influenced Family Routines, Relationships and Technology Use in Families with InfantsThis study explores how the first wave of the COVID‐19 pandemic influenced family routines, relationships and technology use (smartphones and tablet computers) among families with infants. Infancy is known to be an important period for attachment security and future child development, and a time of being susceptible to changes within and outside of the family unit.
Research
Earth dreams: Reimagining ARPA for health of people, places and planetBold new approaches are urgently needed to overcome global health challenges. The proposed Advanced Research Projects Agency for Health (ARPA-H) is intended to provide rapid health breakthroughs.
News & Events
Shopping For Data to Drive DiscoveriesWhat if researchers could shop for different data to help uncover how, when and why chronic conditions such as asthma, obesity, allergies and poor mental health develop?
News & Events
ORIGINS Ch7 News StoryORIGINS featured on Channel 7 News recently with two family stories of how ORIGINS changed their lives.
News & Events
Tips for protecting your baby in the summer heatPaediatrician Dr Lana Bell shares her top tips for keeping your baby or toddler cool, well-hydrated and protected as the temperature soars.
News & Events
Hong Kong researcher highlights importance of nature for children during Joondalup Health Campus visitJoondalup Health Campus welcomed international researcher Dr Tanja Sobko to share her research on the link between mental health and time spent in nature.
News & Events
Early ORIGINS: Disease prevention starts with the early yearsThe Joondalup Health Campus and The Kids are investigating how childhood and adult-onset diseases can be prevented during foetal development and in the early years of life.