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Next-generation Malaria Vaccines Stakeholder Engagement Meetings held at ASTMH

At the American Society of Tropical Medicine and Hygiene (ASTMH) Annual Meetings in 2024 and 2025, our team convened stakeholder engagement sessions on next-generation malaria vaccines.

Reimagining OpenMalaria and Supporting Novel Tools

In this project, we will support malaria control and elimination using OpenMalaria: our in-house, open-source, advanced malaria simulation tool.

Strep A modelling: OpenStrepA

Strep A causes a huge global burden of disease, from sore throats to rheumatic heart disease. Our team is developing a computer simulation model, OpenStrepA, to help researchers tackle this disease.

Vaccine Impact Modelling Consortium (VIMC) supporting Gavi, the Vaccine Alliance

In this project, our team provides malaria vaccine impact predictions to inform vaccine investment strategies for Gavi, the Vaccine Alliance, and their partners.

Julian Heng

Julian is the Program Manager for the Global Disease Modelling team at The Kids Research Institute Australia.

Epke Annelie Le Rutte

Epke is a veterinarian that specializes in infectious disease control, and holds a PhD in human neglected tropical disease (NTD) control and elimination.

Global Disease Modelling

We help shape how the world responds to infectious diseases: guiding vaccine and treatment development, and advising on public health measures to control and eliminate disease. Our mathematical models capture how diseases spread, how severe infections are, and how childhood exposure shapes health across a lifetime.

Effect of maternal prebiotic supplementation on human milk immunological composition: Insights from the SYMBA study

Immunomodulatory proteins in human milk (HM) can shape infant immune development. However, strategies to modulate their levels are currently unknown. This study investigated whether maternal prebiotic supplementation alters the levels of immunomodulatory proteins in HM. 

Vegetation structure drives mosquito community composition in UK's largest managed lowland wetland

The rising burden of mosquito-borne diseases in Europe extends beyond urban areas, encompassing rural and semi-urban regions near managed and natural wetlands evidenced by recent outbreaks of Usutu and West Nile viruses. While wetland management policies focus on biodiversity and ecosystem services, few studies explore the impact on mosquito vectors.

Efficacy thresholds and target populations for antiviral COVID-19 treatments to save lives and costs: a modelling study

In 2023 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was declared endemic, yet hospital admissions have persisted and risen within populations at high and moderate risk of developing severe disease, which include those of older age, and those with co-morbidities. Antiviral treatments, currently only available for high-risk individuals, play an important role in preventing severe disease and hospitalisation within this subpopulation.