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Chronic suppurative otitis media (CSOM) is a leading global cause of potentially preventable hearing loss in children and adults, associated with socioeconomic deprivation. There is an absence of consensus on the definition of CSOM, which complicates efforts for prevention, treatment, and monitoring.
Chronic suppurative otitis media (CSOM), sometimes referred to as chronic otitis media (COM), is a chronic inflammation and often polymicrobial infection of the middle ear and mastoid cavity, characterised by ear discharge (otorrhoea) through a perforated tympanic membrane. The predominant symptoms of CSOM are ear discharge and hearing loss. Systemic antibiotics are commonly used to treat people with CSOM. This is the first update to the review published in 2021, and is one of a suite of seven Cochrane reviews evaluating the effects of non-surgical interventions for CSOM.
PCV10 did not reduce NTHi density in the nasopharynx or middle ear, and was associated with increased pneumococcal nasopharyngeal density
The relationship between early life episodes of otitis media and later behavioural development with adjustment for confounders.
To assess the effectiveness of antibiotics versus antiseptics for people with chronic suppurative otitis media.
To assess the effects of topical antiseptics for people with chronic suppurative otitis media
To assess the effects of systemic antibiotics for people with chronic suppurative otitis media.
To assess the effects of topical antibiotics for people with chronic suppurative otitis media.
To assess the effects of adding a topical steroid to topical antibiotics in the treatment of people with chronic suppurative otitis media
These data provide evidence that otitis-prone children do not have impaired functional cell mediated immunity