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Polygenic risk of ischemic stroke is associated with cognitive ability

Findings from this study indicate that even in the absence of stroke, being at high polygenic risk of ischemic stroke is associated with lower cognitive ability

Increasing incidence of type 2 diabetes in Indigenous and non-Indigenous children in Western Australia, 1990-2012

In this study, we aimed to determine the incidence and incidence rate trends of childhood T2D in Indigenous and non-Indigenous children in WA.

Knowledge translation lessons from an audit of Aboriginal Australians with acute coronary syndrome presenting to a regional hospital

This audit is used as a case study of translating knowledge processes in order to identify the factors that support equity-oriented knowledge translation.

On-the-fly selection of cell-specific enhancers, genes, miRNAs and proteins across the human body using SlideBase

SlideBase, a web tool which offers a new way of selecting genes, promoters, enhancers and microRNAs that are preferentially expressed/used in a specified set of cells/tissues

Fathers’ Commute to Work and Children’s Social and Emotional Well-Being in Germany

Is fathers’ commute to work associated with increases in child social and emotional well-being as measured in Strengths and Difficulties Questionnaires?

Optimization is required when using linked hospital and laboratory data to investigate respiratory infections

Chart review to validate linked microbiological data

Effects of maternal dietary egg intake during early lactation on human milk ovalbumin concentration: A randomized controlled trial

Increased maternal egg ingestion is associated with increased breastmilk ovalbumin, and markers of immune tolerance in infants

Biodiesel exhaust-induced cytotoxicity and proinflammatory mediator production in human airway epithelial cells

Canola biodiesel exhaust exposure elicits inflammation and reduces viability of human epithelial cell cultures in vitro when compared with ULSD exhaust exposure

Asbestos exposure: Challenges for Australian clinicians

Anxiety and the inability to reduce MM risk following exposure or to halt progression of established asbestosis result in significant health care problems

Transforming Life: A Broad View of the Developmental Origins of Health and Disease Concept from an Ecological Justice Perspective

With emerging research involving green space, the microbiome, biodiversity and positive psychology, we discuss ecological justice in the dysbiosphere

IRF7-Associated Immunophenotypes Have Dichotomous Responses to Virus/Allergen Coexposure and OM-85-Induced Reprogramming

High risk for virus-induced asthma exacerbations in children is associated with an IRF7lo immunophenotype, but the underlying mechanisms are unclear. Here, we applied a Systems Biology approach to an animal model comprising rat strains manifesting high versus low susceptibility to experimental asthma, induced by virus/allergen coexposure, to elucidate the mechanism(s)-of-action of the high-risk asthma immunophenotype.

Protection against neonatal respiratory viral infection via maternal treatment during pregnancy with the benign immune training agent OM-85

Incomplete maturation of immune regulatory functions at birth is antecedent to the heightened risk for severe respiratory infections during infancy. Our forerunner animal model studies demonstrated that maternal treatment with the microbial-derived immune training agent OM-85 during pregnancy promotes accelerated postnatal maturation of mechanisms that regulate inflammatory processes in the offspring airways.