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Research

Severity and persistence of asthma and mental health: a birth cohort study

The goal of the current study was to investigate asthma and mental health among youth in the community.

Research

Vitamin D 3 deficiency enhances allergen-induced lymphocyte responses in a mouse model of allergic airway disease

In this study, using a mouse model, we determined whether vitamin D deficiency in utero and during early life modulated the severity of asthma.

Research

Viral infections and atopy in asthma pathogenesis: New rationales for asthma prevention and treatment

Prospective birth cohort studies tracking asthma initiation and consolidation in community cohorts have identified viral infections occurring against a...

Research

Hierarchy and molecular properties of house dust mite allergens

The allergenic load of house dust mite allergy is largely constituted by a few proteins with a hierarchical pattern of allergenicity.

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Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype

Previous analyses of family data from the Tasmanian Longitudinal Health Study provide evidence that this phenotype has a stronger genetic cause than asthma...

Research

Rhinovirus-induced asthma exacerbations and risk populations

Asthma exacerbations are heterogeneous conditions that involve the complex interplay between environmental exposures and innate and adaptive immune function

Research

Toward improved prediction of risk for atopy and asthma among preschoolers: A prospective cohort study

Atopy and asthma are commonly initiated during early life, and there is increasing interest in the development of preventive treatments for at-risk children.

Research

Providing feedback on adherence increases use of preventive medication by asthmatic children

This study investigates the impact of measuring adherence and providing feedback on medication usage by children with unstable asthma.

Research

Toll-like receptor 2 ligands inhibit Th2 responses to mite allergen

There is intense interest in the interaction between microbial compounds and allergy.

Research

UV exposure and protection against allergic airways disease

Asthma is a chronic inflammatory disease of the small and large conducting airway mucosa characterised by Th2 cell immunity.