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Childhood atopy and mental health: a prospective, longitudinal investigationFindings are the first linking atopy (measured by both parent report and objective verification) with increased vulnerability to affective and anxiety problems
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Population-based estimates of the effectiveness of pneumococcal vaccination in AustraliaAustralia’s Childhood Immunisation Register (ACIR) is one of only a handful of national immunisation registers world-wide.
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Global allergy forum and second davos declaration 2013 allergy: Barriers to cure - Challenges and actions to be takenThe epidemic increase in the prevalence of allergic disease, which first started in the industrialized countries in the 1960s, may have reached a peak in the...
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Safety and Immunogenicity of Neonatal Pneumococcal Conjugate Vaccination in Papua New Guinean Children: A Randomised Controlled TrialWe conducted an open randomized controlled trial in Papua New Guinea to compare safety, immunogenicity and priming for memory of 7-valent PCV (PCV7) given in...
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Ontogeny of toll-like and NOD-like receptor-mediated innate immune responses in Papua New Guinean infantsStudies addressing the ontogeny of the innate immune system in early life have reported mainly on Toll-like receptor (TLR) responses in infants living in...
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Febrile respiratory illnesses in infancy and atopy are risk factors for persistent asthma and wheezeThe aim of this study was to explore associations between severe respiratory infections and atopy in early childhood with persisting wheeze and asthma.
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A genomics-based approach to assessment of vaccine safety and immunogenicity in childrenThis methodology has significant potential to identify covert interactions between inflammatory pathways triggered by vaccination, and as such may be a...
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Systems biology and big data in asthma and allergy: recent discoveries and emerging challengesWe describe recent "omic"-level findings, and examine how these findings have been systematically integrated to generate further insight
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Immunoinflammatory responses to febrile lower respiratory infections in infants display uniquely complex/intense transcriptomic profilesthe association between infant LRTI and risk for persistent wheeze/asthma in this cohort is generally stronger for fLRTIs than for other infection categories
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Meta-analysis identifies seven susceptibility loci involved in the atopic marchEczema often precedes the development of asthma in a disease course called the 'atopic march'.