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The high burden of infectious disease and associated antimicrobial use likely contribute to the emergence of antimicrobial resistance in remote Australian Aboriginal communities. We aimed to develop and apply context-specific tools to audit antimicrobial use in the remote primary healthcare setting.
We have demonstrated the potential use of Bayesian Networks in improving antibiotic selection for children with osteomyelitis
The burden and consequences of skin infections for remote living indigenous people are high
These data support that children are not just 'little adults' in the AMR era, and analyses by age group are important to detect differences in antibiotic susceptibility
We have demonstrated that a single dose of a closely related commensal can delay onset of NTHi otitis media in vivo
An optimized, rapid method for creating markerless isogenic mutations that combines Gibson assembly cloning with a new temperature-sensitive plasmid, pLZts
Significant variation in practice, particularly for patients with a severe disease phenotype and antibiotic-resistant profile
We have quantified the relative influence of perinatal risk factors associated with skin infection hospitalisations in WA children
Documenting carer, service provider and healthcare practitioner perspectives on skin infections provides more understanding of the context of treatment decisions
Few children and adolescents receiving BPG as secondary prophylaxis will achieve concentrations >0.02 mg/L for the majority of the time between injections