Skip to content
The Kids Research Institute Australia logo
Donate

Search

Early life arsenic exposure and acute and long-term responses to influenza A infection in mice

Exposure to arsenic in early life has been shown to increase the rate of respiratory infections during infancy, reduce childhood lung function, and increase...

Emerging Early Life Environmental Exposures and Lung Development

In this review article we systematically summarize the evidence for an impact on lung development of 1) maternal ingestion of arsenic contaminated drinking...

In utero exposure to arsenic alters lung development and genes related to immune and mucociliary function in mice

In utero exposure to arsenic via drinking water increases the risk of lower respiratory tract infections during infancy and mortality from bronchiectasis in...

Factors influencing the assessment of lung function in mice with influenza-induced lung disease

The constant-phase model (CPM) is commonly fit to respiratory system input impedance (Z rs) to estimate lung mechanics.

Defective aeroallergen surveillance by airway mucosal dendritic cells as a determinant of risk

A hallmark of atopic asthma is development of chronic airways hyper-responsiveness (AHR) that persists in the face of ongoing exposure to perennial...

Sexual dimorphism in lung function responses to acute influenza A infection

Males are generally more susceptible to respiratory infections; however, there are few data on the physiological responses to such infections in males and...

Boosting airway T-regulatory cells by gastrointestinal stimulation as a strategy for asthma control

The hallmark of atopic asthma is transient airways hyperresponsiveness (AHR) preceded by aeroallergen-induced Th-cell activation.

Risk assessment for respiratory complications in paediatric anaesthesia: a prospective cohort study

Perioperative respiratory adverse events in children are one of the major causes of morbidity and mortality during paediatric anaesthesia.

Mouse Lung Structure and Function after Long-Term Exposure to an Atmospheric Carbon Dioxide Level Predicted by Climate Change Modeling

Climate change models predict that atmospheric carbon dioxide [CO2] levels will be between 700 and 900 ppm within the next 80yrs. In this study we aimed to assess the respiratory structure and function effects of long-term exposure to 890ppm CO2 from preconception to adulthood using a mouse model.

Pharmacological ablation of the airway smooth muscle layer—Mathematical predictions of functional improvement in asthma

Findings provide further proof of concept that pharmacological targeting of airway smooth muscle thickness will be beneficial and may be facilitated by azithromycin