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Evolving Identification of Blood Cells Associated with Clinically Isolated Syndrome: Importance of Time since Clinical Presentation and Diagnostic MRIThis study aimed to identify a CIS peripheral blood signature that may provide clues for potential immunomodulatory approaches early in disease
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UV Irradiation of Skin Regulates a Murine Model of Multiple Sclerosis.The prevalence of multiple sclerosis follows a latitude gradient, with increased disease at higher latitudes.
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Vitamin D deficiency causes airway hyperresponsiveness and increases airway smooth muscle mass in the lungs of female BALB/c miceWe tested whether there is a causal association between vitamin D deficiency, airway smooth muscle (ASM) mass, and the development of airway hyperresponsiveness
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Altered immunity and dendritic cell activity in the periphery of mice after long-term engraftment with bone marrow from ultraviolet-irradiated miceTo investigate the immune capabilities of peripheral tissue DCs generated in vivo from the BM of UV-irradiated mice, chimeric mice were established.
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Maternal vitamin D levels during pregnancy and offspring eating disorder risk in adolescenceThis is the first study to link low gestational vitamin D to increased eating disorder risk in female offspring of Caucasian mothers.
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Topical 1,25-dihydroxyvitamin D3 subverts the priming ability of draining lymph node dendritic cellsThe active form of vitamin D, 1,25-hydroxyvitamin D(3) [1,25(OH)(2)D(3)] is produced in skin following exposure to sunlight
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1,25-dihydroxyvitamin D3 enhances the ability of transferred CD4+ CD25+ cells to modulate T helper type 2-driven asthmatic responsesThe severity of allergic diseases may be modified by vitamin D. However, the immune pathways modulated by the active form of vitamin D, 1,25-dihydroxyvitamin D.
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Genome Sequence of a Lytic Staphylococcus aureus Bacteriophage Isolated from Breast MilkWe identified a double-stranded DNA (dsDNA) bacteriophage appearing to belong to Herelleviridae, genus Kayvirus. The bacteriophage, Biyabeda-mokiny 1, was isolated from breast milk using a clinical isolate of Staphylococcus aureus.
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Ultraviolet irradiation of mice reduces the competency of bone marrow-derived CD11c+Direct UV irradiation of dendritic cells and Langerhans cells reduces their Ag presenting ability. However, the effects of UV on CD11c(+) cells located...
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Immune cell trafficking from the brain maintains CNS immune toleranceEvaluation of fluorescently labeled leukocyte migration in mice revealed that DCs travel via the RMS from the CNS to the cervical LNs (CxLNs), where they...