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Research

The hygiene hypothesis revisited: role of materno-fetal interactions

For 20 years, the hygiene hypothesis has dominated attempts to explain the increasing prevalence of allergic disease. A causal link between maternal innate immu

Research

UV inhibits allergic airways disease in mice by reducing effector CD4 T cells

In human asthma, and experimental allergic airways disease in mice, antigen-presenting cells and CD4(+) effector cells at the airway mucosa orchestrate, and CD4

Research

Decreased fibronectin production significantly contributes to dysregulated repair of asthmatic epithelium

In human asthma, and experimental allergic airways disease in mice, antigen-presenting cells and CD4(+) effector cells at the airway mucosa orchestrate, and CD4

Research

A diagnostic test for scabies: IgE specificity for a recombinant allergen of Sarcoptes scabiei

Scabies infestations are difficult to diagnose clinically and current serologic tests have less than 50% accuracy...

Research

Responsiveness of the human airway in vitro during deep inspiration and tidal oscillation

In healthy individuals, deep inspiration produces bronchodilation and reduced airway responsiveness, which may be a response of the airway wall to mechanical...

Research

Responsiveness of the human airway in vitro during deep inspiration and tidal oscillation

The aim of this study was to examine the in vitro response of isolated human airways to the dynamic mechanical stretch associated with normal breathing.

Research

Airway epithelial repair in health and disease: Orchestrator or simply a player?

This review attempts to highlight migration-specific and cell-extracellular matrix (ECM) aspects of repair used by epithelial cells

Research

Environmental microbial exposure and protection against asthma

This article looks at the clinical implications of the research into microbial exposure & protection against asthma.

Research

Long-term derangement of antigen presenting cell populations in the respiratory tract following Influenza A infection

This project investigates how different populations of cells within the respiratory tract immune system are altered during a viral infection.

News & Events

WA researchers lead global centre to eliminate childhood asthma

An ambitious project that could stop children developing asthma is the centrepiece of a new world-class respiratory research centre launched in Perth.