Partial amelioration of a chronic cigarette-smoke-induced phenotype in mice by switching to electronic cigarettes

Electronic cigarettes ("e-cigarettes") are often marketed as smoking cessation tools and are used by smokers to reduce/quit cigarette smoking. The objective of this study was to assess the health effects of switching to e-cigarettes after long-term smoking in a mouse model and compare these effects with continued smoking, or quitting entirely.

Citation:
Larcombe AN, Chivers EK, Landwehr KR, Berry LJ, de Jong E, Huxley RR, Musk A, Franklin PJ, Mullins BJ. Partial amelioration of a chronic cigarette-smoke-induced phenotype in mice by switching to electronic cigarettes. Arch Toxicol. 2025.

Keywords:
Cigarette smoke; E-cigarette; Lung health; Mouse

Abstract:
Electronic cigarettes ("e-cigarettes") are often marketed as smoking cessation tools and are used by smokers to reduce/quit cigarette smoking. The objective of this study was to assess the health effects of switching to e-cigarettes after long-term smoking in a mouse model and compare these effects with continued smoking, or quitting entirely.